RESEARCH

- Neonatal Cardiac Regenerative Potential and Regulators in Large Animals.

- Role of metabolisms in Heart Regeneration.

- Endogenous and Exogenous Mechanisms that Promote Myocardial Remuscularization in Post Infarction LV Remodeling

BIO

     To be updated.

SELECTED PUBLICATION

1. Nakada Y, Zhou Y, Gong W, Zhang EY, Skie E, Nguyen T, Wei Y, Zhao M, Chen W, Sun J, Raza SN. Single Nucleus Transcriptomics: Apical Resection in Newborn Pigs Extends the Time Window of Cardiomyocyte Proliferation and Myocardial Regeneration. Circulation. 2022 Jun 7;145(23):1744-7.

2. Nakada Y, Nhi Nguyen NU, Xiao F, Savla JJ, Lam NT, Abdisalaam S, Bhattacharya S, Mukherjee S, Asaithamby A, Gillette TG, Hill JA. DNA damage response mediates pressure overload–induced cardiomyocyte hypertrophy. Circulation. 2019 Feb 26;139(9):1237-9.

3. Nakada Y, Canseco DC, Thet S, Abdisalaam S, Asaithamby A, Santos CX, Shah AM, Zhang H, Faber JE, Kinter MT, Szweda LI. Hypoxia induces heart regeneration in adult mice. Nature. 2017 Jan;541(7636):222-7.

4. Zhao M, Nakada Y, Wei Y, Bian W, Chu Y, Borovjagin AV, Xie M, Zhu W, Nguyen T, Zhou Y, Serpooshan V. Cyclin D2 Overexpression Enhances the Efficacy of Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes for Myocardial Repair in a Swine Model of Myocardial Infarction. Circulation. 2021 Jul 20;144(3):210-28.

5. Bishop SP, Zhou Y, Nakada Y, Zhang J. Changes in cardiomyocyte cell cycle and hypertrophic growth during fetal to adult in mammals. Journal of the American Heart Association. 2021 Jan 19;10(2):e017839.